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1.
Arq. ciências saúde UNIPAR ; 27(10): 5853-5862, 2023.
Article in Portuguese | LILACS-Express | LILACS | ID: biblio-1512848

ABSTRACT

A educação em saúde e o acesso à informação são ferramentas estratégicas para a promoção do autocuidado de pessoas vivendo com HIV. Apesar dos grandes avanços científicos, sobretudo quanto ao uso da TARV, ainda existem desafios a serem enfrentados como o preconceito, o estigma e a desinformação da população. Nesse sentido, tal estratégia contribui com a adesão ao tratamento, por meio do esclarecimento de dúvidas a cerca da infecção pelo HIV. Trata-se de um relato de experiência referente às ações de educação em saúde realizadas em serviços especializados de saúde para o tratamento de pessoas vivendo com HIV. Os participantes do projeto foram capacitados e realizaram ações de educação em saúde, para abordar temas relacionados ao HIV/Aids e para o esclarecimento de dúvidas a respeito da terapia antirretroviral. Conclui-se que a integração dos serviços de saúde com as instituições de ensino se constitui com uma importante estratégia para o desenvolvimento de reflexões críticas acerca da temática, bem como para auxiliar nos cuidados direcionados às pessoas que vivem com HIV. PALAVRAS-CHAVE: Educação em Saúde; HIV; Terapia Antirretroviral; Adesão ao Tratamento.


Health education and access to information are strategic tools for promoting self-care for people living with HIV. Despite the great scientific advances, especially regarding the use of ART, there are still challenges to be faced, such as prejudice, stigma and misinformation of the population. In this sense, such a strategy contributes to adherence to treatment, by clarifying doubts about HIV infection. This is an experience report regarding health education actions carried out in specialized health services for the treatment of people living with HIV. Project participants were trained and carried out health education actions to address issues related to HIV/AIDS and to clarify doubts about antiretroviral therapy. It is concluded that the integration of health services with educational institutions constitutes an important strategy for the development of critical reflections on the subject, as well as to assist in the care directed to people living with HIV.


La educación sanitaria y el acceso a la información son herramientas estratégicas para promover el autocuidado de las personas que viven con VIH. Apesar de los grandes avances científicos, especialmente en lo que respecta al uso de las TAR, todavía quedan desafíos por afrontar, como los prejuicios, el estigma y la desinformación de la población. En este sentido, dicha estrategia contribuye a la adherencia al tratamiento, al aclarar dudas sobre la infección por VIH. Este es un relato de experiencia sobre acciones de educación en salud realizadas en servicios de salud especializados para el tratamiento de personas que viven con VIH. Los participantes del proyecto fueron capacitados y realizaron acciones de educación en salud para abordar temas relacionados con el VIH/SIDA y aclarar dudas sobre la terapia antirretroviral. Se concluye que la integración de los servicios de salud con las instituciones educativas constituye una estrategia importante para el desarrollo de reflexiones críticas sobre el tema, así como para coadyuvar en la atención dirigida a las personas que viven con VIH.

2.
BMC Womens Health ; 22(1): 423, 2022 10 26.
Article in English | MEDLINE | ID: mdl-36284340

ABSTRACT

BACKGROUND: Metabolic syndrome (MetS) is a group of diseases characterized by insulin resistance. MetS has high prevalence among women, which is impacted by food intake. MetS is related to high level of inflammation; however, the impacts of whole diets on biochemical and anthropometrical markers and the effects on MetS need to be further elucidated. In this case, the objective of this study was to assess the relationship between food intake, biochemical and anthropometrical markers in women with MetS. METHODS: This is a cross-sectional study, in which 1 hundred and 22 women participated in the assessment of biochemical (glycated hemoglobin, glycaemia, insulin, uric acid, total cholesterol, HDL-c, LDL-c, triglycerides, C-reactive protein) and anthropometrical (body mass, height, waist circumference - WC) variables. Participants also performed blood pressure and 24-hour dietary recall assessments. Out of the 122 participants, 44 (36%, age: 59 ± 11 years) had MetS and were included in the analysis. RESULTS: The consumption of monounsaturated fats had direct relationship with glycaemia (b = 7.48), whereas the consumption of fibers had inverse relationship with body mass (b = - 0.71) and WC (b = - 0.56). CONCLUSION: The intake of monounsaturated fats and fiber was related to higher blood sugar levels and lower body mass and WC, respectively. These relationships elucidate and highlight the significance and importance of adequate diet in women with MetS.


Subject(s)
Insulins , Metabolic Syndrome , Female , Humans , Middle Aged , Aged , Metabolic Syndrome/epidemiology , Blood Glucose/analysis , Cholesterol, HDL , Glycated Hemoglobin , Cross-Sectional Studies , Uric Acid , Cholesterol, LDL , C-Reactive Protein/analysis , Body Mass Index , Waist Circumference , Triglycerides , Biomarkers , Risk Factors
3.
Rev. Saúde Pública Paraná (Online) ; 3(2): 74-93, abr. 2020.
Article in Portuguese | SESA-PR, Coleciona SUS, CONASS, LILACS | ID: biblio-1252778

ABSTRACT

Diabetes mellitus tipo 2 é uma das maiores causas de óbito por doenças crônicas não transmissíveis, com relevante impacto econômico no sistema de saúde. O atendimento interprofissional é cada vez mais discutido para a recuperação e promoção da saúde. O objetivo desse estudo foi avaliar usuários com diabetes mellitus tipo 2 submetidos a intervenção uni ou interprofissional. Vinte usuários foram selecionados aleatoriamente, separados em dois grupos e submetidos a atendimentos uni ou interprofissional. Não foram observadas diferenças para as variáveis antropométricas e laboratoriais entre os dois grupos. Contudo, a variação percentual (momento inicial e final) de todas as variáveis estudadas foi mais benéfica para usuários da intervenção interprofissional. A incorporação dessa modalidade de atendimento mostrou-se viável, promovendo atenção integral aos usuários, otimização da vinda dos usuários a Unidade Básica de Saúde e das estruturas físicas. Com maior tempo de intervenção e número de usuários, futuros estudos podem apresentar resultados ainda mais promissores. (AU)


Type 2 diabetes is considered one of the most important cause of death by chronic non-communicable disease, with relevant economic impact in the health system. Interprofessional care is an increasingly modality for the health recovery and promotion. The aim of this study was to evaluate type 2 diabetic patients submitted to uni or interprofessional intervention. Twenty users were randomly selected, separated into two groups and submitted to uni or interprofessional care. No differences were observed for the anthropometric and laboratory variables between the two care groups. However, the percentage variation of all studied variables (initial and final moments) was more beneficial for patients submitted to interprofessional intervention. The incorporation of this type of assistance proved to be feasible, promoting comprehensive care to users, optimizing the arrival of users to the Basic Health Unit and physical structures. More pronounced results can be obtained with longer intervention time and greater number of patients. (AU)


Subject(s)
Humans , Primary Health Care , Health Systems , Diabetes Mellitus, Type 2
4.
Tempus (Brasília) ; 12(2): 259-271, nov. 2, 2019.
Article in Portuguese | LILACS | ID: biblio-1434846

ABSTRACT

Trata-se de uma reflexão teórico-prática com objetivo de relatar a experiência de uma equipe multiprofissional na assistência à saúde da mulher na atenção secundária. O presente trabalho aponta que a atenção à saúde da mulher tem se tornado uma área prioritária no contexto das políticas de saúde com foco na atenção integral, humanizada e de qualidade, visando garantir o bem-estar da mulher no seu ciclo vital e melhorar os coeficientes de morbimortalidade. Tendo em vista a construção de uma visão multidisciplinar da assistência à saúde da mulher, surge a Residência Multiprofissional em Saúde da Mulher, que tem como objetivo formar profissionais aptos a realizar ações de caráter multidisciplinar e interdisciplinar para a promoção, prevenção e recuperação da saúde da mulher em idade reprodutiva nos diferentes níveis de atenção, propiciar intervenções críticas no trabalho em equipe e melhorar a qualidade de vida da mulher com base nos princípios e diretrizes do Sistema Único de Saúde. (AU)


This theoretical-practical reflection aims at reporting the experience of a multi-professional team in women's health secondary care. The present study shows that women's health care has become a priority area in the context of health policies focused on comprehensive, humanized quality care, striving to ensure the well-being of women in their life cycle and to improve coefficients of morbimortality. With the intent to building a multidisciplinary vision of women's health care, the Multi-professional Residency in Women's Health emerges, in order to train professionals capable of performing multidisciplinary and interdisciplinary actions for the promotion, prevention and recovery of the health of women of reproductive age at different levels of care, to provide critical interventions in teamwork and to improve the quality of women's life based on the principles and guidelines of the Unified Health System. (AU)


Se trata de una reflexión teórico-práctica con el objetivo de relatar la experiencia de un equipo multiprofesional en la asistencia a la salud de la mujer en la atención secundaria. El presente trabajo apunta que la atención a la salud de la mujer se ha convertido en un área prioritaria en el contexto de las políticas de salud con foco en la atención integral, humanizada y de calidad, con el objetivo de garantizar el bienestar de la mujer en su ciclo vital y mejorar los coeficientes de morbimortalidad. Con el fin de construir una visión multidisciplinaria de la asistencia a la salud de la mujer, surge la Residencia Multiprofesional en Salud de la Mujer, que tiene como objetivo formar profesionales aptos para realizar acciones de carácter multidisciplinario e interdisciplinario para la promoción, prevención y recuperación de la salud de la mujer. la mujer en edad reproductiva en los diferentes niveles de atención, propiciar intervenciones críticas en el trabajo en equipo y mejorar la calidad de vida de la mujer con base en los principios y directrices del Sistema Único de Salud. (AU)


Subject(s)
Patient Care Team , Secondary Care , Women's Health
5.
Rev. SPAGESP ; 17(1): 110-123, 2016.
Article in Portuguese | LILACS, Index Psychology - journals | ID: lil-791898

ABSTRACT

Este estudo teve como objetivo compreender as vivências e os significados emocionais atribuídos ao comer em mulheres obesas que participaram de um programa para redução de peso com equipe multiprofissional. Foi realizado um estudo qualitativo com o auxílio de grupos focais como um facilitador para o surgimento de diferentes discursos acerca do tema. Os resultados foram codificados em quatro categorias. Verificou-se que essas mulheres se utilizam do alimento como uma forma de tamponar o "vazio" que sentem ao exibir corpos fora do ideal estético, trazendo-lhes sofrimento. Os aspectos sociais e psíquicos envolvidos na obesidade não têm sido levados em consideração tanto na compreensão como na forma de tratamento geralmente proposto para as mulheres que se encontram acima do peso.


This study aimed to understand the experiences and emotional meanings assigned to eating by obese women who participated in a program for weight reduction with a multi-professional team. A qualitative study was carried out with the help of focus groups as a facilitator for the emergence of different discourses on the topic. Results were encoded into four categories. It was found that these women use food as a way to fill up the "emptiness" they feel for displaying bodies that do not fit into the aesthetic ideal, which makes them suffer. The social and psychological aspects involved in obesity have not been taken into account both in understanding and in the form of treatment usually offered to women who are overweight.


Este trabajo tiene por objetivo comprender las vivencias y los significados emocionales atribuidos a comer en mujeres obesas que participaron de un programa para reducción de peso con equipo multiprofesional. Fue realizado un estudio cualitativo con el auxilio de grupos focales, un facilitador para el surgimiento de diferentes discursos acerca del tema. Los resultados fueron codificados en cuatro categorías. Verificamos que las mujeres se utilizan del alimento como una forma de tapar el "vacío" que sienten, exhibiendo cuerpos fuera del ideal estético, ocasionándoles sufrimiento. Los aspectos sociales y psíquicos envueltos en la obesidad no se ha tenido en cuenta, tanto en la comprensión como en la forma de tratamiento generalmente propuesto para las mujeres que se encuentran arriba del peso.


Subject(s)
Adolescent , Adult , Middle Aged , Body Image , Feeding and Eating Disorders , Obesity , Patient Care Team
6.
Rev. SPAGESP ; 17(1): 110-123, 2016.
Article in Portuguese | Index Psychology - journals | ID: psi-69531

ABSTRACT

Este estudo teve como objetivo compreender as vivências e os significados emocionais atribuídos ao comer em mulheres obesas que participaram de um programa para redução de peso com equipe multiprofissional. Foi realizado um estudo qualitativo com o auxílio de grupos focais como um facilitador para o surgimento de diferentes discursos acerca do tema. Os resultados foram codificados em quatro categorias. Verificou-se que essas mulheres se utilizam do alimento como uma forma de tamponar o "vazio" que sentem ao exibir corpos fora do ideal estético, trazendo-lhes sofrimento. Os aspectos sociais e psíquicos envolvidos na obesidade não têm sido levados em consideração tanto na compreensão como na forma de tratamento geralmente proposto para as mulheres que se encontram acima do peso.


This study aimed to understand the experiences and emotional meanings assigned to eating by obese women who participated in a program for weight reduction with a multi-professional team. A qualitative study was carried out with the help of focus groups as a facilitator for the emergence of different discourses on the topic. Results were encoded into four categories. It was found that these women use food as a way to fill up the "emptiness" they feel for displaying bodies that do not fit into the aesthetic ideal, which makes them suffer. The social and psychological aspects involved in obesity have not been taken into account both in understanding and in the form of treatment usually offered to women who are overweight.


Este trabajo tiene por objetivo comprender las vivencias y los significados emocionales atribuidos a comer en mujeres obesas que participaron de un programa para reducción de peso con equipo multiprofesional. Fue realizado un estudio cualitativo con el auxilio de grupos focales, un facilitador para el surgimiento de diferentes discursos acerca del tema. Los resultados fueron codificados en cuatro categorías. Verificamos que las mujeres se utilizan del alimento como una forma de tapar el "vacío" que sienten, exhibiendo cuerpos fuera del ideal estético, ocasionándoles sufrimiento. Los aspectos sociales y psíquicos envueltos en la obesidad no se ha tenido en cuenta, tanto en la comprensión como en la forma de tratamiento generalmente propuesto para las mujeres que se encuentran arriba del peso.


Subject(s)
Humans , Female , Obesity , Body Image , Weight Reduction Programs
7.
Rev. enferm. UFPE on line ; 10(7): 2319-2327, 2016. ilus, tab
Article in Portuguese | BDENF - Nursing | ID: biblio-1367492

ABSTRACT

Objetivo: descrever o conhecimento por um grupo de mulheres em relação à obesidade como fator de risco para o câncer de mama. Método: estudo descritivo, transversal, com 40 mulheres obesas. Os dados foram coletados por visitas domiciliares, com um questionário, entre outubro a novembro de 2013. A análise dos dados foi por frequência simples e porcentagem. Os dados foram discutidos com a literatura. Resultados: 55% das mulheres não conheciam nenhum fator de risco relacionado ao câncer de mama e nenhuma identificou a própria obesidade como fator de risco. Sobre o autoexame das mamas, apenas uma mulher desconhecia esta técnica e 67,5% a realizavam periodicamente. A mamografia era realizada anualmente por 57,5% das mulheres. Conclusão: grande parte das mulheres desconhecia ou tinha conhecimento restrito acerca dos fatores de risco, e principalmente, não identificou a própria obesidade como fator de risco para o câncer de mama.(AU)


Objective: to describe the knowledge by a group of women in relation to obesity as a risk factor for a breast cancer. Method: descriptive cross-sectional study, with 40 obese women. Data were collected through home visits, with a questionnaire between October and November of 2013. The analysis of the data was by simple frequency and percentage. The data was discussed with the literature. Results: 55% of the women were not aware of any risk factor related to breast cancer and none of them identify own obesity as a risk factor. About breast auto exams, only one was unaware of this technique and 67.5% periodically performed. The mammography were made annually by 57.5% of women. Conclusion: most of the women didn't know or Had restricted knowledge about the risk factors, and mainly did not identify them own obesity as a risk factor for breast cancer.(AU)


Objetivo: describir el conocimiento por un grupo de mujeres en relación a la obesidad cómo un factor de riesgo para el cáncer de mamá. Método: estudio descriptivo, transversal con 40 mujeres obesas. Los datos fueran colectados por visitas domiciliarias, con un cuestionario entre octubre y noviembre de 2013. Los análisis de los datos fueran por frecuencia simple y porcentaje. Los datos fueran discursos con la literatura. Resultados: 55% de las mujeres no conocían ningún factor de riesgo relacionado con el cáncer de mamá y ninguna identificó la propia obesidad cómo un factor de riesgo. Sobre él examen de las mamás, apenas una mujer desconocía ésta técnica y 67,5% las hacían periódicamente. La monografía era hecha anual por 57,5% de las mujeres. Conclusión: Una gran parte de las mujeres desconocía o tenían el conocimiento restricto acerca de los factores de riesgo, e principalmente no ha identificado la propia obesidad cómo un factor de riesgo para el cáncer de mamá.(AU)


Subject(s)
Humans , Female , Adolescent , Adult , Middle Aged , Women , Breast Neoplasms , Mammography , Health Knowledge, Attitudes, Practice , Risk Factors , Women's Health , Breast Self-Examination , Obesity , Epidemiology, Descriptive , Cross-Sectional Studies , Surveys and Questionnaires
8.
Ann Nutr Metab ; 66(1): 19-25, 2015.
Article in English | MEDLINE | ID: mdl-25500634

ABSTRACT

BACKGROUND: The prevalence of obesity has risen dramatically and the World Health Organization estimates that 700 million people will be obese worldwide by 2015. Approximately, 50% of the Brazilian population above 20 years of age is overweight, and 16% is obese. AIM: This study aimed to evaluate the differences in the expression of PPARα target genes in human peripheral blood mononuclear cells (PBMCs) and free fatty acids (FFA) in obese and non-obese individuals after 24 h of fasting. We first presented evidence that Brazilian people exhibit expression changes in PPARα target genes in PBMCs under fasting conditions. METHODS: Q-PCR was utilized to assess the mRNA expression levels of target genes. RESULTS: In both groups, the FFA concentrations increased significantly after 24 h of fasting. The basal FFA mean concentration was two-fold higher in the obese group compared with the non-obese group. After fasting, all genes evaluated in this study showed increased expression levels compared with basal expression in both groups. CONCLUSION: However, our results reveal no differences in gene expression between the obese and non-obese, more studies are necessary to precisely delineate the associated mechanisms, particularly those that include groups with different degrees of obesity and patients with diabetes mellitus type 2 because the expression of the main genes that are involved in ß-oxidation and glucose level maintenance are affected by these factors.


Subject(s)
Fasting/metabolism , Leukocytes, Mononuclear/metabolism , Obesity/genetics , PPAR alpha/genetics , Adult , Aged , Brazil , Fatty Acids, Nonesterified/blood , Gene Expression , Humans , Male , Middle Aged , Obesity/blood , Polymerase Chain Reaction , RNA, Messenger , Young Adult
9.
Int J Food Sci Nutr ; 63(1): 49-58, 2012 Feb.
Article in English | MEDLINE | ID: mdl-21728920

ABSTRACT

The objective was to develop a cereal bar product rich in isoflavones and soy protein to be used in diets for controlling dyslipidaemia. A soy snack bar with 39.88 g/100 g dietary fibre, 34.25 g/100 g protein, 100.39 mg/100 g isoflavones and 245.47 kcal/100 g was produced. The shelf life of the product was tested over a period of 6 months. The hardness, water activity and darkness of the snack bars increased with storage time. Clinical trial was carried out to evaluate the effectiveness of the soy snack bar on the lipid profiles of 22 dyslipidaemic subjects for a period of 45 days. There was a decrease in levels of triglycerides (TGs) (- 20%) and an increase in high-density lipoprotein cholesterol (HDL-c) (+8%) comparing with baseline values. Therefore, relatively high intakes of soy protein and isoflavones in moderately hypercholesterolaemic subjects (>200 mg/dl) may have a moderately beneficial effect on plasma lipid profiles, as TG and HDL-c levels, without additional diet restrictions.


Subject(s)
Cholesterol, HDL/blood , Hypercholesterolemia/diet therapy , Isoflavones/therapeutic use , Soybean Proteins/therapeutic use , Triglycerides/blood , Adult , Color , Edible Grain , Female , Food Preservation , Humans , Hypercholesterolemia/blood , Isoflavones/pharmacology , Male , Middle Aged , Seeds , Soybean Proteins/pharmacology , Water
10.
Semina cienc. biol. saude ; 32(2): 143-154, jul.-dez. 2011. tab
Article in Portuguese | LILACS | ID: lil-678676

ABSTRACT

O presente estudo avaliou a ingestão dietética e o estado nutricional de indivíduos com hepatite C com e sem tratamento antiviral. Os indivíduos participantes foram distribuídos em três grupos amostrais: Grupo Controle (G1) com 26 indivíduos saudáveis, Grupo 2 (G2) com 30 indivíduos com hepatite Csem tratamento antiviral, e Grupo 3 (G3) com 26 indivíduos com hepatite C em tratamento antiviral. Os indicadores antropométricos mostraram que a média de peso e porcentagem de gordura corpórea do G1 e G2 e o índice de massa corpórea do G2 e G3 estavam aumentados. Os valores séricos de ASTe ALT estiveram aumentados no G2 e G3 não sendo essa diferença significativa, considerando p < 0,05. A ingestão média energética (Kcal/dia) e de proteína (g/kg/d) estava adequada. O consumo médio de carboidrato foi acima do recomendado e a porcentagem média de lipídeo foi adequado, mas o G2consumiu mais lipídeo e fibras que o G3 sendo estatisticamente diferentes; entretanto a quantidade de fibras ingerida foi abaixo do recomendado nos três grupos. Conclui-se que o estado nutricional dos indivíduos com hepatite C é de sobrepeso. Uma vez tendo elevado percentual de gordura corpórea, esse diagnóstico pode ser fator de risco importante para doenças cardiovasculares e outras complicaçõesassociadas, além de afetar diretamente a qualidade de vida desses indivíduos.


The aim of this study was to evaluate the dietary intake and the nutritional status of individuals infected with Hepatitis C virus both with and without antiviral treatment. The individuals were consisted of data into three groups: The Control Group (G1): 26 healthy individuals, Group 2 (G2): 30 individualsinfected with hepatitis C without antiviral treatment and Group 3 (G3): 26 individuals with hepatitis C receiving antiviral treatment. The anthropometric index showed that the weight average and % of body fat from G1 and G2, as well as (BMI), Body Mass Index, from G2 and G3 were higher. The AST and ALT values in serum were enhanced at G2 and G3, though this is not a significant difference, considering p < 0,05. The mean energy intake (Kcal/day) and of protein (g/kg/d) was adequate. The carbohydrate mean intake was above the recommended, and % lipids mean was adequate, however G2 had a higher intake of lipids and fibers than G3 being statistically different, yet the amount of fibersintake was below the recommended in all three groups. In conclusion to that, the nutritional status of the individuals with hepatitis C is of overweight with high percent of body fat. This diagnosis can be an important risk factor to cardiovascular diseases and other associated complications besides directlyaffect the individual quality of life.


Subject(s)
Humans , Male , Female , Adult , Anthropometry , Diet , Nutritional Status , Hepatitis C
11.
Regul Toxicol Pharmacol ; 59(3): 412-22, 2011 Apr.
Article in English | MEDLINE | ID: mdl-21295629

ABSTRACT

The development of various types of cancer results from the interaction among endogenous, environmental and hormonal factors, where the most notable of these factors is diet. The aim of the present study was to determine the antigenotoxic, anticarcinogenic, phagocytic and immunomodulatory activities of Agaricus blazei. The test antigenotoxicity (Comet Assay) and anticarcinogenic (Test of Aberrant Crypt Foci) assess changes in DNA and/or intestinal mucosa that correlate to cancer development. Tests of phagocytosis in the spleen and differential count in blood cells allow the inference of modulation of the immune system as well as to propose a way of eliminating cells with DNA damage. Supplementation with the mushroom was carried out under pre-treatment, simultaneous treatment, post-treatment and pre-treatment+continuous conditions. Statistical analysis demonstrated that the mushroom did not have genotoxic activity but showed antigenotoxic activity. Supplementation caused an increase in the number of monocytes and in phagocytic activity, suggesting that supplementation increases a proliferation of monocytes, consequently increasing phagocytic capacity especially in the groups pre-treatment, simultaneous and pre-treatment+continuous. The data suggest that A. blazei could act as a functional food capable of promoting immunomodulation which can account for the destruction of cells with DNA alterations that correlate with the development of cancer, since this mushroom was demonstrated to have a preventive effect against pre-neoplastic colorectal lesions evaluated by the aberrant crypt foci assay. According to these results and the literature, it is believed that supplementation with A. blazei can be an efficient method for the prevention of cancer as well as possibly being an important coadjuvant treatment in chemotherapy.


Subject(s)
Agaricus , Antimutagenic Agents/pharmacology , Antineoplastic Agents/pharmacology , Immunologic Factors/physiology , Phagocytosis/drug effects , Phagocytosis/physiology , Plant Extracts/pharmacology , Agaricus/genetics , Agaricus/immunology , Animals , Antimutagenic Agents/isolation & purification , Antimutagenic Agents/metabolism , Antineoplastic Agents/blood , Antineoplastic Agents/isolation & purification , Comet Assay/methods , DNA Damage/drug effects , DNA Damage/physiology , Immunologic Factors/blood , Immunologic Factors/isolation & purification , Male , Mice , Plant Extracts/blood , Plant Extracts/isolation & purification
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